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Hepatic HDAC3 regulates systemic iron homeostasis and ferroptosis via the hippo signaling pathway

20 Histone H3K9 methylation, especially H3K9me2 and trimethylated histone 3 lysine 9 (H3K9me3), generally regulates heterochromatin formation and gene inhibition

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In a January 2023 article, Denmark investigators reported their examinations into the genetic makeup of 34 elderly (mostly aged 10 years) Swedish cavaliers, 19 of which had no mitral valve disease (MVD) or were in Stage B1 or B2, and 15 dogs in Stage C with severe MVD