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Orcioli-Silva et al., 2021

The role of endoxifen would be reviewed solely with respect to targets downstream from dystrophin, and the goal of endoxifen as a therapy is palliative, with the aim of slowing disease progression, rather than curative

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confirmed that a single intranasal dose of Semax in rats produced marked increases in hippocampal BDNF protein and TrkB receptor phosphorylation, alongside improved performance in conditioned avoidance testing establishing BDNF/TrkB modulation as the primary candidate mechanism for Semaxs cognitive research profile and anchoring this compound as a BDNF-upregulating neuropeptide research tool