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With the development of high-throughput sequencing and bioinformatics technology, it had been found that Helicobacter pylori was not the only microbe that survives in the stomach, and that there were other types of microbes

Earlier studies found rare, functional mutations in genes encoding for NRXN1, SHANK3, and SHANK2, all of which are proteins that affect the functioning of synapses and have been linked to other, known genetic disorders ( Table 1 Genetic biomarkers in ASD (see text for references)