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Li et al 33 found that, in rats, oral NAC inhibited matrix metalloproteinase (MMP)-9 and MMP-2 production, which are key factors in neuropathic pain

The figure presents estimated pooled average treatment effects based on random effects meta-analysis, with 95% confidence intervals, for groups of studies classified by their type of disease, mean baseline GFR, median baseline UACR, and mean chronic slope in the control arm