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Therefore, key challenges for future research include balancing short-term symptom control with long-term complication risks, developing non-dopaminergic therapies to address non-motor symptoms, and exploring combination drug strategies to achieve synergistic therapeutic effects

doi: 10.3201/eid1510.090310 58 WinthropKLIsemanM

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The association between symptoms and ammonia concentration remains unclear, with a significant proportion of individuals with HA cases remaining apparently asymptomatic