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The S-chiral ester of NPAA (S-NPAA) was two-fold more effective than the R-chiral ester (R-NPAA) in depleting GSH, increasing oxidative stress, inducing apoptosis, and decreasing cell viability in tumorigenic prostate LNCaP cells but had little effect on non-tumorigenic RWPE-1 cells

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Parts of this work were funded by grants from the DFG (German Research Foundation)Projektnummer 209933838SFB 1052 (project B1 to M.B.) and by Deutsches Zentrum fr Diabetesforschung (DZD, Grant: 82DZD00601 to M.B.)

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1986 Jun;24(6):693-8 (9) Dieguez C, Jordan V, Harris P, Foord S, Rodriguez-Arnao MD, Gomez-Pan A, Hall R, Scanlon MF

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