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Semaglutide is a clinician-guided GLP-1 medication that helps regulate appetite and support metabolic balance

The cell lysate was centrifuged at 20,000 rpm (48,000 g ) for 1 h at 4 C to remove cell debris

Other FDA-approved drugs, including donepezil, galantamine, rivastigmine, and memantine, have demonstrated cognitive benefits but are frequently associated with gastrointestinal disturbances, dizziness, agitation, and, in some cases, severe hepatotoxicity, as observed with tacrine (Marucci et al., 2021