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Inverse Association between Habitual Polyphenol Intake and Incidence of Cardiovascular Events in the PREDIMED Study

8B), which is partly due to accelerated proliferation and altered metabolism 25,26,27 , additional increases in intracellular ROS levels, which are tolerable for normal cells, become lethal to most cancer cells 15,27 (Fig

Despite of contradictory results reported until now in different trials (see a recent review, [65]), the easiness to acquire these products for patients and their natural origin, most of them nutritional supplements, makes them a good choice in poor symptomatic CIPN or intermittent therapy between cycles of chemotherapy

This was associated with decreased GSH levels, increased caspase 3, 8 and 9 activity, and DNA damage (Figure 1c)