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In vitro studies commonly evaluate its influence on intracellular pathways such as PI3K/Akt and MAPK/ERK signaling, which are associated with cellular growth, metabolic regulation, and protein synthesis in laboratory models

Polygalae radix shortens the circadian period through activation of the CaMKII pathway

The tail intensity (% tail DNA), defined as the percentage of DNA migrated from the head of the comet into the tail, was used as a measure of DNA damage induced