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499 A and phosphorylated Tau (p-Tau) neurofibrillary lesions lead to the pathology of neurons that display oxidative damage, impaired Ca2+ processing, reduced DNA repair, dysfunction of lysosomal and mitophagy, all of which have a positive correlation with the age-related NAD + decline

Its associated with significant brain damage and potentially life-threatening complications

Engineering exosome-like nanovesicles derived from asparagus cochinchinensis can inhibit the proliferation of hepatocellular carcinoma cells with better safety profile