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de Castro-Silva C, de Bruin VM, Cunha GM, Nunes DM, Medeiros CA, et al

However, passive targeting that takes advantage of the unique physiological features of specific tissues, such as tumours, to enhance the effective accumulation of nanoparticles [141, 144, 145]

Figure 4 8 Translational outlook: analogs, safety liabilities, and delivery strategies Erastin has demonstrated antitumor activity in several malignancies, including gastric and colorectal cancer (69, 70), and the inflammatory, iron-loaded, oxidative microenvironment shared by many tumors and EMS provides a coherent theoretical basis for applying this strategy to EMS (71, 72)

Plasma therapy may have limited effects since several factors are connected with the disease, including the fact that aggregation of -synuclein is not the sole factor that contributes to the progression of PD [50]