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Responses to Hypoxia: How Fructose Metabolism and Hypoxia-Inducible Factor-1a Pathways Converge in Health and Disease

Its administration can lead to noteworthy cardiovascular side effects, such as elevated heart rate and blood pressure, and has been linked to an augmented risk of heart attack, stroke, and withdrawal symptoms upon abrupt cessation

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Repeated oral dose of OTA induced oxidative stress in mice kidneys, which was concluded from increased lipid peroxidation parameters (conjugated dienes and trienes, and malondialdehyde), downregulation of glutathione S-transferase and, upregulation of glutathione peroxidase genes