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A 1 mg oral dose results in a C max of 12-22 g/L

GEMSTING@Gel, a degradable reactive oxygen speciesbased hydrogel system, was designed to codeliver gemcitabine and the interferon gene stimulator DMXAA (5,6dimethylxanthenone 4 acetic acid) to tumour sites and regulate the immunosuppressive TME by synergistically activating innate immunity and promoting the infiltration of cytotoxic T lymphocytes (209)

In some cases, these reactions may lead to hyperpigmentation, scarring, or prolonged inflammation especially if sun exposure is repeated or the reaction is not recognised and managed early