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For targeted therapeutic support during severe symptom flares or intense detoxification protocols, some functional medicine providers may recommend temporarily increasing the dose to 300 mg or 400 mg per day, though this should always be done under medical supervision

Estimated GFR (eGFR) was calculated according to gender, age and the concentration of serum Cr according the Japanese equation Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) 62

Stem Cell Research & Therapy , 12 (1), 430

Os efeitos de um uso crnico, as interaes medicamentosas potenciais e os efeitos em populaes especficas (gestantes, crianas, pessoas imunodeprimidas) so amplamente desconhecidos