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Mov Disord (2010) 25(15):26216

While regular caffeinated coffee reduced total sleep time and worsened sleep quality, decaffeinated coffee allowed these sleep parameters to remain at optimal levels

As afore reported, subjects were prevalently assessed under pharmacological treatment, a stable condition at the time of the investigation, that could have an impact, albeit putatively modest, on results

Unlike HSCs, which divide and differentiate at a much slower rate and can rely on glycolysis and the limited OXPHOS possible in the bone marrow niche for their energy needs (10), LSCs divide more rapidly, generating a higher energetic demand compared to HSCs