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It was previously approved by the FDA for diagnostic evaluation and treatment of pediatric GH deficiency and is now widely used off-label in research and clinical settings to address adult-onset GH insufficiency and age-related hormonal decline

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For some users, subtle changes may even appear within 1-2 weeks of routine application

A landmark 2009 study found that GHK-Cu reversed the gene expression of older skin cells to look more like young skin cells, upregulating collagen and downregulating inflammatory genes