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Finkelstein JD, Harris BJ, Martin JJ: Methionine metabolism in mammals: Concentrations of metabolites in rat tissues

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This downregulation subsequently inhibits NLRP3 inflammasome activation, leading to upregulation of GPX4/SLC7A11 or downregulation of ACSL4/ALOX15, and ultimately suppressing both ferroptosis and neuroinflammation

A key limitation of this study is that while quercetins bioavailability and tissue distribution have been previously reported, we did not directly measure its concentrations in the liver or ovary