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doi: 10.1056/NEJMoa1012740 120 RenWZhaoLSunY

Your doctor needs to understand the exact cause of your B12 deficiency

Beyond lowering blood sugar, metformin may also: Cause weight loss Help manage polycystic ovarian syndrome (PCOS) symptoms Improve insulin sensitivity Manage gestational diabetes Manage prediabetes So, while berberine may be an option for someone who prefers not to take prescription medication or cannot tolerate them, metformin remains the more effective, safe and proven choice

a) Representative IMC images of Ki-67, Collagen I (large vessels), and CD68 (macrophages/microglia) positive cells in regions occupied by cells in one of the three metabolic states in GB tumours