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First time: Beginner protocol with gradual dose increase over 4 weeks

In the meantime, results from earlier trials provide insight into the key benefits observed so far: Appetite suppression and weight reduction: A 26-week phase 2 study, involving 706 overweight and obese participants without T2D, showed a weight reduction of -9.7% (-22.7 lb) with 2.4 mg/week and -10.8% (-25.4 lb) with 4.5 mg/week of cagrilintide

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As of 2026, the paper has not been formally retracted, but the Expression of Concern remains in force