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The primary endpointchange in Clinical Dementia Rating Sum of Boxes (CDR-SB)showed no significant difference between groups

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Estrogen receptors alpha (ER) and beta (ER) belong to the so-called classical family of estrogen receptors, while the G protein-coupled estrogen receptor 1 (GPER-1) represents a non-classical estrogen receptor mainly located in the plasma membrane

Measure whether daily maternal administration of 50 g vitamin B 12 from early pregnancy until 6 months postpartum improves the infants z-scores length for age, weight for age and weight for length at 12 months