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Pioglitazone, an ACSL4 inhibitor, showed significant cardiovascular benefits in a Phase III trial (NCT00091949) involving insulin-resistant patients with a history of IS or transient ischemic attack (TIA)

4 ROS in disease pathophysiology Because of cellular metabolism, eukaryotic cells continuously generate endogenous ROS

A 2021 retrospective study examined knee injections in 16 patients with various types of knee pain

When the volume of transplanted tumor reached approximately 150 mm 3 , mice were randomly divided into five groups (five mice per group), injected with PBS, MONs@MOF-199, free DOX/SOR, D/S@MM, and D/S@SPMM (5 mg DOX/kg and 1 mg SOR/kg) via tail vein once every three days within an interval of 21 days