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During early childhood, characterized by rapid synapse formation, methylation is highly plastic during the first 5 years of life

The over the counter drug is used by millions across the world, and increasingly by pregnant women (up to 65%)

In vitro , aggregated A enhances both NMDA and kainate receptor-mediated L-glu toxicity, most likely by interfering with neuronal calcium homeostasis (Mattson et al., 1992)