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In an in vitro incubation of MMBD containing rat urine with calf thymus DNA in the presence of S9, a guanine DNA adduct of MMBD (dG-MMBD) was detected as the major adduct formed

Alfalfa saponins can rescue cell viability, elevate the activity of antioxidant enzymes, and downregulate the activities of LDH and MDA in H 2 O 2 -induced cells

Furthermore, the fractions of rescued worms occupying the pathogen lawn were comparable to those of the wild type (Fig

5.5 Conclusion and future direction Recognizing the limitations of conventional delivery routes in targeting the CNS, IN administration provides a non-invasive alternative that not only bypasses the BBB but also avoids hepatic first-pass metabolism