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The eye and lens provide a useful, accessible system to study general countermeasures the body might have for defending itself against UV radiation. The current study was done in collaboration with the Iladevi Cataract and IOL Research Center in Ahmedabad, India

Moreover, resveratrol orchestrates multimodal physiological regulation through concerted modulation of core signaling networks, principally governing insulin signaling pathway dynamics, xenobiotic metabolism via cytochrome P450 enzyme systems, and steroidogenic axis coordination encompassing estrogen signaling, progesterone-mediated oocyte maturation, and steroid hormone biosynthesis, thereby systemically ameliorating HA and IR (87)

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Mutation screening of 75 candidate genes in 152 complex I deficiency cases identifies pathogenic variants in 16 genes including NDUFB9