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Achouba, A., Dumas, P., Ouellet, N., Lemire, M

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(2) the specific CI inhibitor IACS-010759 was recently reported to promote neurotoxicity, making this an unattractive agent for combination therapy in CRC given the neurotoxicity long-recognized with oxaliplatin treatment 51

For instance, the release of damage-associated molecular patterns (DAMPs) such as HMGB1 during ferroptosis activates receptors like AGER/RAGE, stimulating the NF-B pathway ( 4 Ferroptosis in recurrent miscarriage A variety of pathophysiological mechanisms contribute to RM, including genetic, anatomical, hormonal, and immunological factors