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NICE-aligned management typically involves: Addressing modifiable risk factors (smoking cessation, weight loss, increased physical activity, alcohol reduction) Optimising management of underlying conditions (diabetes, hypertension, depression) Trial of PDE5 inhibitor therapy Referral to specialist services (urology/andrology) if first-line treatments fail or where structural/neurological/endocrine causes are suspected Consideration of psychosexual therapy where appropriate Men should be reassured that ED is a medical condition with effective treatments, and seeking help through proper channels ensures safety, appropriate investigation of underlying causes, and access to evidence-based therapies

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Examples of serotonergic drugs: Here are some serotonergic drugs: SSRIs, such as fluoxetine (Prozac) SNRIs, such as venlafaxine (Effexor XR) tricyclic antidepressants, such as amitriptyline certain other antidepressants, such as mirtazapine (Remeron) triptans for migraine, such as sumatriptan (Imitrex) the anxiety drug buspirone lithium (Lithobid) certain opioids, such as fentanyl (Fentora, Actiq) Steps you or your doctor may take: If you take Adderall with a serotonergic drug, your doctor may prescribe a dosage of Adderall thats lower than usual

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