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The collagenase solution was blocked with complete medium and passed through a 100 m filter

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They, therefore, suggested administering a second dose of PRP where necessary at about three months in the case of partial recovery as a boost dose [23]

Normal and expected reactions include a brief stinging or burning sensation during or immediately after injection, mild redness or warmth at the injection site lasting a few minutes, and small temporary lumps that resolve within 30 to 60 minutes as the solution disperses through subcutaneous tissue