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However, in conditions like ischemic stroke and spinal cord injury, CHAC1 promotes neuronal damage by inducing ferroptosis through the depletion of GSH, a critical antioxidant, exacerbating oxidative stress and worsening the injury (Mei et al., 2017

intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency

Aging Cell 22:e13807

Pros: Supports sending emails and attachments Custom or random addresses Long history of reliability No signup required Cons: Interface feels dated Emails expire after ~1 hour (extendable) Higher chance of blocks on some platforms Best Use Cases: Temporary scenarios needing to send replies or attachments, like testing forms or anonymous communication