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KaplanRFTrevinoRPJohnsonGMLevyLDornbushRHuLTet al

While a dominant-negative effect might have been anticipated, heterozygous mice are normal, while homozygous mice have severe defects of cornea, mildly impaired growth, skin fragility, and mild skin extensibility a substantially different phenotype from classical EDS due to COL5A1 haploinsufficiency

Furthermore, greater growth inhibition of EGFR-positive BRAF mutated tumours was measured following a single dose of Albu-LiTE-HB construct compared to the Fc-less LiTE format and a full-length anti-EGFR monoclonal antibody in a new AlbuMus RAG1 knockout model introduced in this work