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CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma

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Changes to the gut microbiota during dysbiosis have now been linked to a myriad of diseases such as IBD, irritable bowel syndrome (IBS), obesity and rheumatoid arthritis [118121]

Another study suggested that oxidative stress-induced 4-hydroxy-2-nonenal (HNE) triggers mitochondrial translocation of AIFM2, promoting apoptosis in cardiac tissues of both mice and humans 40