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These changes correlate with increased GSH levels and decreased ACSL4 expression, thus mitigating ferroptotic cell death in IL-1stimulated chondrocytes and preserving cartilage integrity (187)

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Ascorbic acid (vitamin C) and -tocopherol (vitamin E) obtained mostly from diet are also important non-enzymatic erythrocyte antioxidants [19]

Analysis of calcium ion (Ca 2+ ) levels in macrophages To detect the intracellular Ca 2+ content, 143B cells were incubated with PBS, Ru(II)-OH, NP2, and NP4 (Ru 10 M) for 6 h