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Clinically meaningful weight loss typically becomes apparent after 4 to 8 weeks of treatment, once therapeutic doses are reached and steady-state drug levels are achieved

Subcellular localization prediction indicated that the majority of proteins were localized in the nucleus (21.79%), cytoplasm (16.67%), and extracellular space (14.10%) (Figure 4E)

The relationship between excessive iodine during pregnancy and adverse pregnancy complications