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This is evident from studies showing that FSH could not promote CYP19, LHR, and StAR expression in the presence of an IGF inhibitor (113)

Maalouf M, Sullivan PG, Davis L, Kim DY, Rho JM

The PPAR agonists rosiglitazone and pioglitazone were recently found to reduce the levels of 2-HG and H3K4me3 in the colon of mice with colitis and to regulate GSH and ROS levels in lamina propria lymphocytes by modulating GLS1/2-HG/H3K4me3 signaling in mouse models of colitis and asthma ( Table 1 )