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Also, CAR-T cells directed to PDPN by a construct composed of NZ-1-based single-chain variable fragments and CD28, 4-1BB and CD3 intracellular domains have shown good efficiency against glioma cells both in vitro and in vivo glioma xenografts (277)

Abbreviations AI: Artificial intelligence CNC: Cellulose nanocrystals DFU: Diabetic foot ulcer EPS: Extracellular polymeric substances GOx: Glucose oxidase LCA: Life cycle assessment MMPs: Matrix metalloproteinases NC: Nanocellulose PLA: Polylactic acid ROS: Reactive oxygen species SCFA: Short-chain fatty acids TMAO: Trimethylamine N-oxide ECM: Extracellular matrix CFU: Colony-forming units References Collaborators GBDCoD

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In studies, people lost around 11 to 13% of their body weight