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In fact, some studies have even suggested that L-Carnitine may have a positive effect on skin health by reducing inflammation and improving hydration

Emerging strategies include selecting efflux-insensitive payloads like topoisomerase I inhibitors, as demonstrated by T-DXds success in DESTINY-CRC01, contrasting with MMAE-based failures (122)

Table 2 summaries the microbial metabolites of EC that have demonstrated anti-inflammatory effects, along with their precursors, experimental models, and underlying mechanisms