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The dual role of iron in CNS physiology and pathology underscores the need for interdisciplinary research to refine diagnostics and therapies

224 Heart failure (HF) Currently, over 64 million patients worldwide have HF, 225 and HF is a growing area of interest

Strengthening the research on the pathogenesis and intervention measures of the secondary injury is potential therapeutic options to improve the outcome of TBI (3, 4)