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Accordingly, we observed that lactational body weight loss was significantly exacerbated by increased energy or AA intake during gestation, with the HE-HAA group exhibiting the most pronounced weight loss due to the cumulative effects of elevated energy and AA intake

However, prolonged or high-dose ketamine exposure induces a compensatory upregulation of NMDARs, increasing intracellular calcium ion influx and ROS production, ultimately leading to neuronal apoptosis ( In animal studies, antagonism of NMDA receptors in intermediate neurons of the forebrain and thalamus reduces GABAergic function

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Third: structural support