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In the TSHR-immunized murine model of Graves disease, Treg depletion (particularly CD25) induced thyroid lymphocytic infiltrates with transient or permanent hypothyroidism (19.2)

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One trial demonstrated that a 4-week course of calcipotriolbetamethasone combination therapy led to Physician Global Assessment (PGA) 0/1 (clear or nearly clear) rates of 72.6%, 56.5%, and 66.7% in mild, moderate, and severe psoriasis patients, respectively (93)