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Journal of the American Dental Association (JADA) jada.ada.org Research data comparing multimodal analgesia (Tylenol + Ibuprofen) to opioid-based pain management

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These findings promote the hypothesis of melatonin acting against SQSTM1/p62, the cargo receptor that incites autophagic degradation or clockophagy of BMAL1/ARNTL and, by extension, the resulting ferroptosis [374]