mthfr gene mutation and b12 injections What are the Different Types of B12? Clinical, phenotypic and genetic landscape

It is believed that up to 90% of vegans and vegetarians are deficient in B12 (R, Se and T, 2014), and therefore recommended that they should use supplements to ensure their continued health

Once reconstituted, it has a short half-life due to proteolytic degradation, requiring immediate use or careful refrigeration

This typically involves: Intrinsic factor antibodies (highly specific for pernicious anaemia, though sensitivity is only 50%) [12] [28] Gastric parietal cell antibodies (more sensitive but less specific) Coeliac serology if malabsorption is suspected Consideration of upper gastrointestinal endoscopy in selected cases, particularly with autoimmune gastritis/pernicious anaemia NICE guidance emphasises that treatment should not be delayed whilst awaiting antibody results if clinical features strongly suggest deficiency, as irreversible neurological damage can occur

If you have already been diagnosed with vitamin deficiency, B12 vitamin shots can help you, not only with your deficiency, but with weight loss, as well