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However nonalcoholic fatty liver disease (NAFLD) is increasingly recognized as a cause of isolated abnormalities in serum transaminase concentrations

For weight loss on their own, the evidence does not support it

Differentiation of organoids The cBOs were generated from the above-mentioned iPSCs (AD4 harbouring PSEN1-E9 mutation, isogenic control corrected for PSEN1-E9 mutation and healthy control stem cell lines) (Supplementary Fig