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Cell (2017) 169:1187200

Excessive autophagy can lead to metabolic stress and degradation of cellular components, which exacerbates the structural destruction and functional decline of tissues ( 2 O 2 -induced autophagy with a decreased expression of autophagy marker proteins LC3-II and Beclin-1

Weber DD, Aminzadeh-Gohari S, Tulipan J, Catalano L, Feichtinger RG, Kofler B

Ill tell you, I get most of my iron from plants and I have the genes for hemochromatosis, which means I absorb too much iron from my food and I can eat ridiculous amounts of iron from plants and my iron levels, if I donate blood like once every two years, dont get out of hand