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Holanda AON, de Oliveira ARS, Cruz KJC, et al

& Driever, W

This oxidative stress results in lipid peroxidation, protein oxidation, and DNA damage, further injuring neurons and aggravating seizure activity ( 2.2 The key impact of oxidative stress in neuronal damage during epilepsy Owing to the key roles of neuroinflammation and oxidative stress in epilepsy, targeting these pathways presents a promising therapeutic approach

High-fat or high-sugar meals whilst not contraindicated, these may worsen gastrointestinal side effects, particularly during the dose escalation phase