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A 2025 study published in Frontiers in Pharmacology used a fermentation product derived from Lactobacillus paracasei (formally Lacticaseibacillus paracasei ) to investigate TMA reduction in trimethylaminuria models

ARS may reduce the secretion of VEGF and IL-8 induced by TNF or hypoxia, as well as the expression of HIF-1, possibly by inhibiting the activation of PI3K/AKT