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For example, in kidney allografts undergoing the transition from AKI to CKD, the level of p21 is elevated [70]

Studies have also shown that long-term oral administration of baclofen can improve ASD-like behaviors in VPA-exposed mice after weaning, and prenatal intervention in offspring can also improve ASD-like behaviors, demonstrating the potential of early intervention with GABAB receptor agonists in treating ASD (143)

While the exact mechanism remains under investigation, current evidence suggests that AIT first suppresses basophils and mast cells, followed by a shift towards the formation of allergen-specific Tregs, the depletion of reactive mediators, and the stimulation of allergen-specific IgG production

12(7):e529-e541 Al Malki, Monzr M