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The increase in the activity or quantity of EnaC induces an increase in sodium reabsorption by epithelial cells, which plays a role in the development of Liddle syndrome

Genes in the cellular response to xenobiotic stimulus and glutathione metabolic processes categories ( Nqo1 , Gstm1 Gstm4 , Gsta1 , Gsta2 , Srxn1 ) are characteristic of NRF2-regulated OSR

While we also observed a slight increase in Il4 expression within the Th2 cluster ( Figure S4E ) and in whole skin lysate ( Figure 6E ), the enhancement of the Th1 response was substantially more pronounced

doi: 10.1094/MPMI-06-17-0138-R 75 ScheibnerF.MarillonnetS.BttnerD