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However, tandem mass spectrometry with electrospray ionisation has been used to measure TMA and TMAO following derivatisation of trimethylamine with ethyl bromoacetate to form ethyl betaine bromide

The clearest human evidence points to an effect on peripheral thyroid hormone action

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456,457 Anti-CTLA-4 antibodies are confined to trigger intracellular signal pathways, including cell cycle regulation pathways which do not overlap with anti-PD-1/PD-L1 antibodies