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An NSG-PiZ mouse model was developed, and hepatocyte proliferation was assessed via immunofluorescence staining for hepatocyte growth factor in liver sections post-mRNA-LNP infusion (Fig

In both in vitro (0.5 M for 24 h) and in vivo (141 mol/kg/day for 14 days) settings, SF mitigated high glucose-induced apoptosis by inhibiting the upregulation of apoptotic markers and the downregulation of antiapoptotic maker Bcl-2 protein in hippocampal neurons exposed to high glucose (126)

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In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate