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consequently, astrocyte dysfunction can impair synaptic transmission, induce excitotoxicity, and cognitive and motor impairments (Dodge et al., 2013)

Throughout the treatment period, the mice in the CDCZA group experienced a consistent increase in body weight, rising from 19.6 g on day 0 to 22.4 g on day 12, suggesting that the CDCZA treatment did not result in notable systemic side effects for the mice