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4.1.1 Local delivery of RNA-LNPs A straightforward way to bypass hepatic accumulation of LNPs is to change the administration route from intravenous delivery to other administration routes, which could shorten the delivery path and enhance accessibility to the target cells (Figure 3) (Chenthamara et al., 2019

IV therapy circumvents this entire process, delivering vital nutrients directly to the cells that need them most

The positive modulation of the gut microbiota in fish in turn resulted in improvement in the growth, gut health, nutrient metabolism, immune response and disease resistance of the host (Qi et al., 2024)